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American PieMovie | 1999

American Pie is a 1999 American coming-of-age teen sex comedy film directed and co-produced by Paul Weitz (in his directorial debut) and written by Adam Herz. It is the first film in the American Pie theatrical series and stars an ensemble cast that includes Jason Biggs, Chris Klein, Alyson Hannigan, Natasha Lyonne, Thomas Ian Nicholas, Tara Reid, Mena Suvari, Eddie Kaye Thomas, Seann William Scott, Eugene Levy, Shannon Elizabeth and Jennifer Coolidge. The plot centers on five classmates (Jim, Kevin, Oz, Finch, and Stifler) who attend East Great Falls High. With the sole exception of Stifler, who has already lost his virginity, the youths make a pact to lose their virginity before their high school graduation.

American PieMovie | 1999

Despite insiders claiming it to be a potential sleeper hit, Universal Pictures sold off the foreign rights in an attempt to recoup its budget. American Pie was sold successfully to foreign distributors at the Cannes International Film Festival.[18] It earned $18.7 million during its opening weekend and defeated Wild Wild West to reach the number one spot.[19] The film grossed $235,483,004 worldwide,[3][20] $132,922,000 of which was from international tickets. In the United States and Canada, it grossed $102,561,004 and was the twentieth highest-grossing film of 1999. In Germany, distributed by Constantin Films, it was the most successful theatrical release of 2000 with a gross of $33.5 million.[21][22]

We've tracked the top players on a weekly basis all year long,now it's our chance to tell you who were the best in the nation ateach position in 1999. We picked three teams of players and anhonorable mention squad based on nominations by SIDs andcoaches.

WR Sean Eaton, Randolph-Macon The school's and ODAC's single-season leader for receptions with95, Eaton caught for 1,289 yards, breaking the school andconference records there as well. The senior finished 1999 with 15receiving touchdowns. He posted season highs of 13 receptionsagainst Guilford and 182 yards against Catholic.

DL David Monaghan, Allegheny The senior played in all 42 games over his four-year career,starting 32, and totaled 53 solo tackles, 20 for loss and 10 sacksin 1999. Three and a half of those sacks came in one game, againstOhio Wesleyan Sept. 25. Monaghan also broke up five passes,intercepted two and recovered two fumbles.

DB Marvin Deal, Western Maryland The three-year Centennial Conference interceptions leader pickedoff eight more passes in 1999 and broke up five more. The seniorrecorded 41 tackles (21 solo), including four tackles for loss.

RET Joshua Carter, Muhlenberg The sophomore returned kickoffs for 981 yards in 1999, which isbelieved to be a Division III record, and averaged 35 yards perreturn. He scored four touchdowns on 61 total punt and kickoffreturns.

WR Adam Marino, Mount Union Marino finished with 88 catches for 1724 yards and 20 touchdownsin 13 games for the Purple Raiders, after having surpassed his 199814-game totals in the first 10 games of 1999.

OL Josh Hostetter, Pacific Lutheran Helped block for the national champions, including the uniquesystem in which Lutes linemen call their own blocks. PacificLutheran ran for 228.6 yards per game in 1999.

The American Inventors Protection Act (AIPA) was enacted November 29, 1999, as Public Law 106-113 and amended by the Intellectual Property and High Technology Technical Amendments Act of 2002 (Public Law 107-273) enacted November 2, 2002. The material presented on this web site reflects this enacted law.

State and local health departments reported a provisional total of 100confirmed measles cases to CDC in 1999. This total equals the record low number ofcases reported in 1998 (1). Since 1997, measles incidence in the United States hasremained

Imported cases accounted for 33% of all measles cases reported in1999, continuing a trend since 1992 of an increased proportion of imported cases (Figure 1). Imported measles cases occurred among 14 international visitors and 19U.S. residents exposed to measles while traveling abroad.

In 1999, the proportion of all cases classified as unknown source cases was34%; this proportion has been decreasing since 1995 (Figure 2). Of the 34unknown-source cases, 10 were isolated cases with no epidemiologic link to any other measlescase. The remaining 24 cases occurred in four outbreaks.Geographic and Temporal Patterns of DistributionDuring 1999, 31 states and the District of Columbia reported no confirmedmeasles cases. Ten states accounted for 86% of cases. Unknown source cases werereported from nine states. During 33 weeks, all reported measles cases wereimportation-associated (no unknown source cases were reported), including cases reportedduring a continuous period of 12 weeks (weeks 19--30).

Of the 3140 counties in the United States, 16 (0.5%) reported measles casesof unknown source. In 10 of these counties, unknown source cases occurred during1-week periods. Five counties reported unknown source cases for periods between2 and 4 weeks, and one county reported unknown source cases during11 noncontinuous weeks.Age and Vaccination StatusDuring 1999, persons aged >20 years accounted for 32% of reportedmeasles cases. Elementary school-aged children and adolescents (aged 5--19 years)accounted for 26% of cases, followed by preschool children (aged 1--4 years) with 24% ofcases,and infants (aged

Among the 100 persons with measles, 16 had been vaccinated with one ormore doses of measles-containing vaccine. Measles vaccination rates were 0%among infants, 17% among preschool-aged children, 19% among school-agedchildren including adolescents, and 22% among personsaged>20 years. Among U.S. residents with measles, 15 (17%) of 86 were vaccinated, compared with one (7%) of 14among inter-national visitors.OutbreaksEleven measles outbreaks (a cluster of three or more cases) with a median offour cases per outbreak were reported in 1999 and accounted for 63% of all casesreported during 1999. An epidemiologic link to an imported measles case was documentedin seven of the outbreaks.

The largest outbreak (15 cases) during 1999 occurred in Bedford, Virginia.The index case-patient was an adult who had traveled through Europe, Africa, andthe Middle East. Fourteen cases occurred in three generations of spread. Settingsof transmission included the household and church of the index case-patient andhealth-care settings.

Reported by: State and local health depts. Measles Virus Section, Respiratory and EntericViruses Br, Div of Viral and Rickettsial Diseases, National Center for Infectious Diseases;Measles Elimination Activity, Child Vaccine Preventable Diseases Br, Epidemiology and SurveillanceDiv, National Immunization Program; and an EIS officer, CDC.Editorial Note: The findings in this report document a continuing trend of recordlow numbers of measles cases and a high percentage of imported cases, suggestingthat measles is not endemic in the United States. In 1999, as in the previous 2 years,fewmeasles cases of unknown source were reported and these cases did notcluster temporally or geographically in patterns that would suggest a chain ofendemic transmission. Virologic data indicated that only imported virus strainswere transmitted in the United States in 1999.

During March 2000, CDC convened a consultation of measlesexperts to evaluate data on the elimination of endemic measles from the United States. The dataindicated that, during 1997--1999, measles incidence has remained low(90% with the first dose of measles vaccine in children aged19--35 months since 1996 (2) and 98% coverage among children entering school(3). In 48 states and the District of Columbia, a second dose of measles vaccine is requiredfor school entry (4). A national serosurvey indicated that 93% of persons aged >6years have antibody to measles (5).

  • On the basis of these findings, the experts concluded that measles is nolonger endemic in the United States. However, because endemic measles couldbe reestablished if vaccination coverage declines, efforts should continue to ensurethat coverage remains high and that surveillance is strong. In addition, because ofthe continued threat of imported measles, the experts encouraged strengthenedsupport for global measles control and eradication of measles.References CDC. Epidemiology of measles---United States, 1998. MMWR 1999;48:749--52.

  • CDC. National vaccination coverage levels among children aged 19--35 months---UnitedStates 1998. MMWR 1999;48:829--30.

  • Peter G. Childhood immunizations. N Engl J Med 1992;327:1794--1800.

  • CDC. State immunization requirements, 1998--1999. Atlanta, Georgia: US Department ofHealth and Human Services, CDC, 1999.

  • Hutchins S, Bellini W, Kruszon-Moran D, Schrag S, McQuillan G, Strine T. Measlesimmunity among persons >6 years of age, United States, 1988--1994. Abstracts of the AmericanPublic Health Association 127th annual meeting. Washington, DC: American PublicHealth Association, 1998:424.

* Imported=cases among persons who were infected outside the UnitedStates; indigenous=cases in persons infected in the United States.

Design, Setting, and Participants This cross-sectional study used data from 50.3 million US death certificates from 1999 to 2018 to create age-specific linear regression models and assess weekly mortality fluctuations above a seasonal baseline associated with RSV and influenza. Statistical analysis was performed for 1043 weeks from January 3, 1999, to December 29, 2018.

Before projecting the proportion of people treated with implants 5 and 10 y out from the last NHANES data set, we compared the average annual change in log odds of having an implant between the unadjusted and covariate-adjusted models, and the difference was negligible. Because there was little evidence of confounding by sociodemographic factors, including age, we used unadjusted logistic regression models to regress presence of any implant versus year. After fitting the model, we added new observations for the years 2021 and 2026 and derived predicted values (and corresponding 95% prediction interval; StataCorp 2013; Inlow 2018) for all years. To vary assumptions about how the temporal trend would be predicted to continue into the years 2021 and 2026, we proposed 4 simple scenarios. Specifically, we assumed that the increase in implant prevalence would 1) stop, 2) slow, 3) continue at the same pace, or 4) continue at an increased pace. We operationalized these assumptions by varying which years were included in the model fitting. For all 4 scenarios, we used logistic regression to regress the presence of any implant versus year. For the first scenario, we assumed that the proportion of eligible patients with any implant would remain the same as the fitted value (i.e., average probability estimated by the regression line for all years) in 2015 to 2016. For the other 3 scenarios, we predicted the future prevalence based on the slope of the regression line, using all years from 2000 to 2016 for scenario 2, excluding 2015 to 2016 in scenario 3 (in case it was aberrantly high), and excluding 1999 to 2000 and 2001 to 2002 in scenario 4 (because the proportion with implants did not really start taking off until 2003 to 2004 or later). We plotted all observed percentages, fitted percentages, and projected percentages over time (in years). Because we did not adjust these models for covariates, the projected populations are assumed to have similar population distributions by age, insurance type, and so on. We know that this assumption may not be true. However, we picked several otherwise realistic scenarios that provide a range of rough estimates for implant use through 2026. The least realistic scenario is also the most conservative, predicting that the increase in prevalence of implants might abruptly stop. 041b061a72

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